{"id":379,"date":"2024-08-19T23:16:59","date_gmt":"2024-08-19T23:16:59","guid":{"rendered":"https:\/\/simpathic.eu\/?page_id=379"},"modified":"2024-08-19T23:17:52","modified_gmt":"2024-08-19T23:17:52","slug":"read-more-tiny-tim","status":"publish","type":"page","link":"https:\/\/simpathic.eu\/?page_id=379","title":{"rendered":"Read more Tiny Tim"},"content":{"rendered":"\t\t
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SIMPATHIC
Tiny TIM<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Tim is waiting for a cure<\/strong><\/p>

Tim is suffering from a rare neurological disease. Just like other patients with rare neurometabolic and neuromuscular disorders, Tim is waiting for medication to cure him, or at least ease his symptoms. Medication development is costly and time-consuming: 12 years at an average cost of 1.2 billion euros before entering the market is no exception. The scarcity of patients with rare diseases like Tim\u2019s impacts the process: trials and studies can take much longer with a lower anticipated return on investment. There simply are less patients that will buy the drug compared to more prevalent diseases. Yet patients like Tim \u2013 or Tina or Them \u2013 need medication now. What if we were to do things radically differently to speed up the process and repurpose existing medication tailored to Tim\u2019s symptoms?<\/p>

Disclaimer: <\/em>Although we use \u2018Tim\u2019 and \u2018he\u2019 to refer to an imaginary patient to represent all patients impacted by SIMPATHIC, these patients will not all be men. The word \u2018Tim\u2019 or \u2018he\u2019 should be read as including both men, women (Tiny Tina) and individuals who do not identify themselves as either (Tiny Them).<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Research consortium introduces a Tiny-Tim<\/strong><\/p>

That is the aim of the SIMPATHIC consortium. We are developing a new approach to expedite the development of existing drugs for groups of patients with rare neurological, neurometabolic and neuromuscular disorders like Tim. From a tube of Tim\u2019s blood or a small piece of his skin, we will obtain Tim\u2019s cells and convert them into one type of brain cells. Let\u2019s call this collection of cells a Tiny-Tim. This group of converted cells is not a clone of Tim, yet a cellular model of one type of brain cells (or an organoid consisting of different types of brain cells) that can be used to test several drugs at the time using highly automated procedures. We aim to test a single drug to cure or ease common symptoms of multiple diseases. For not only Tim can get the best medication he so desperately needs, but this medication might also be suitable for other patients suffering from different neurological diseases with similar symptoms. The Tiny-Tim combined with the highly automated procedures enable the researchers to expedite the matching-making process between the repurposed medication and the impact on disease symptoms.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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SIMPATHIC Tiny TIM Tim is waiting for a cure Tim is suffering from a rare neurological disease. Just like other patients with rare neurometabolic and neuromuscular disorders, Tim is waiting for medication to cure him, or at least ease his symptoms. Medication development is costly and time-consuming: 12 years at an average cost of 1.2 […]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-379","page","type-page","status-publish","hentry"],"featured_image_src":null,"featured_image_src_square":null,"_links":{"self":[{"href":"https:\/\/simpathic.eu\/index.php?rest_route=\/wp\/v2\/pages\/379","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/simpathic.eu\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/simpathic.eu\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/simpathic.eu\/index.php?rest_route=\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/simpathic.eu\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=379"}],"version-history":[{"count":4,"href":"https:\/\/simpathic.eu\/index.php?rest_route=\/wp\/v2\/pages\/379\/revisions"}],"predecessor-version":[{"id":385,"href":"https:\/\/simpathic.eu\/index.php?rest_route=\/wp\/v2\/pages\/379\/revisions\/385"}],"wp:attachment":[{"href":"https:\/\/simpathic.eu\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=379"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}